Official French records indicate that the Armenier family has been tending vines in Châteauneuf-du-Pape since the 1300's. Today, winemaker-sisters Catherine Armenier and Sophie Estevenin continue to write history with the wines of Domaine de Marcoux.

In 1990, the Domaine became the first in the Châteauneuf-du-Pape to implement biodynamic farming practices. Their youngest vines are 40- to 60-years-old, and in short, the sisters do as little as possible to the harvested grapes. This domaine, as critic Stephen Tanzer put it, is "the essence of Châteauneuf-du-Pape."

In 2003, Robert Parker named Sophie and Catherine on his list of "Wine Personalities of Year," writing, "Over the last 12 years, the biodynamically farmed vineyard has risen to the top of Châteauneuf-du-Pape's quality hierarchy. The two red wines produced have been stunning, with the regular cuvée of Châteauneuf-du-Pape one of the finest in the appellation, and the limited production Cuvée Vieilles Vignes one of the world's truly magnificent wines."